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KMID : 0603519970020010019
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Journal of Korean Association of Cancer Prevention
1997 Volume.2 No. 1 p.19 ~ p.26
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Inhibition of Chemically Induced Carcinogenesis and Mutagenesis by Some Natural Products and Synthetic Derivatives
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Park Kwang-Kyun
Lee Ja-Hyun
Oh Seung-Hee
Lee Won-Young
Sohn Yeo-Won
Surh Young-Joon
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Abstract
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Chemoprevention has been shown to be an extremly promising approach to the prevention of invasive cancer. Through the identification of chemopreventive agents that block or reverse the process of carcinogenesis, new strategies of early intervention can be developed for patients at high risk that potentially prevent the onset of invasive and metastatic phases of cancer. This articles reviews the our result in chemoprevention research, including natural products such as capsaicin, dially sulfide and gingerol, and structurally related compounds such as chlorophyllin, dehydroparadol and 2-(allythio)pyrazine.
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KEYWORD
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Chemoprevention, Capsaicin, Diallyl sulfide, Gingerol, Parasol chlorophyllin, Dehydroparadol, 2-(allythio)pyrazine, Vanilloids
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